Global Sequencing Reagents Market, By Technology (Sanger Sequencing, Third Generation Sequencing, NGS), Type (Library Kits, Template Kits, Control Kits, Sequencing Kits, Others), End-User, and Application (Oncology, Reproductive Health, Clinical Investigation, Agrigenomics & Forensics, etc) (Clinical Research, Academic Research, Hospitals & Clinics, Pharmaceutical & Biotechnology Companies, Others), Country (United States, Canada, Italy, United Kingdom, France, Mexico, Germany, Spain, Netherlands, Belgium, Switzerland, Turkey, Russia, Rest of Europe, India, Japan, China, South Korea, Australia, Singapore, Indonesia, Philippines, Malaysia, Thailand, Rest of Asia- Pacific, Brazil, Argentina, Rest of South America, South Africa, Saudi Arabia, United Arab Emirates, Egypt, Israel, Rest of the Middle East & Africa) Industry Trends and Forecast to 2028.
Insights into the Sequencing Reagents Market Share
Oxford Nanopore Technologies, Thermo Fisher Scientific, Inc., BGI, Pacific Biosciences of California, Inc., Illumina, Inc., QIAGEN, F. Hoffmann-La Roche AG, Agilent Technologies, Inc., Fluidigm Corporation, ArcherDX, Inc., Takara Bio, Inc., and Bioline are prominent market participants.
Market participants are making substantial investments to bolster their market presence and preserve their competitive edge. In addition, key companies participate in a variety of collaborative models, product development, and geographic expansion strategies in untapped regions.
For instance, in March 2019, Agilent Technologies introduced the Magnis NGS Prep System, a new library preparation system for NGS technology. This new system includes reagents and protocols that make it simple to test genomic DNA for complex genetic mutations and multiple genes.
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Type of Reagent Insights
In terms of revenue, the sequencing kits segment dominated the market in 2018 and is anticipated to maintain its lead throughout the forecast period. Due to the presence of major high throughputs platforms, such as the MiniSeq, MiSeq, iSeq, NextSeq, HiSeq X, and NovaSeq series from Illumina; the PGM, IonS5, and Ion Proton System from Thermo Fisher Scientific; and the MinION, GridION X5, and PromethION from Oxford Nanopore, this is the case.
In the coming years, the market for library kits is anticipated to be significantly propelled by innovations that enhance library preparation workflow. Utilizing liquid handling platforms and their accessories for heating, cooling, shaking, and magnetic bead manipulations to automate library construction yields high-quality libraries for whole-genome sequencing.
Due to the high usage rate of reagents in clinical research and the development of cancer diagnostics and therapeutics, oncology accounted for the largest share of the sequencing reagents market in 2018. It has become easier for oncologists to access genetic information and heterogeneity associated with cancer and cancer-related genes due to the rapid development of sequencing technologies.
NGS analysis of tumor transcriptomics, genomics, and epigenomics influences biomarker discovery for cancer diagnostics and tumour stratification in a positive manner. The development of precision oncology, which stimulates new oncological clinical trial designs for the detection of genetic vulnerabilities in patients, has also benefited from the enhancement of sequencing capabilities.
The identification of pathogens by means of high-throughput technologies and bioinformatics yields in-depth knowledge of antimicrobial resistance, virulence, and disease transmission. In the field of clinical and public health microbiology, this drives the adoption of reagents. The clinical investigation segment is anticipated to experience the highest growth during the forecast period.
The market has been segmented based on end-use into academic research, clinical research, hospitals and clinics, pharmaceutical and biotechnology companies, and others. Academic research captured the largest revenue share due to the presence of a large number of universities and research centers engaged in the provision of molecular biology courses utilizing NGS techniques. The demand for NGS reagents is anticipated to increase as a result of the Ph.D. scholarships offered by these centers.
The clinical research segment is expected to grow at the highest rate during the forecast period. This market segment is anticipated to be influenced by the increasing penetration of technology-based diagnostic tests with a high throughput that has CLIA waivers or is undergoing clinical approval.
The conventional Sanger method and its associated reagents remain a popular option for clinical applications and scientific investigation. NGS reagents are increasingly used in clinical diagnostics because their single-nucleotide resolution can detect the smallest possible mutations (SNPs) without the need for additional mutation-specific information. In recent years, technological advancements have facilitated the combined detection of larger abnormalities and SNPs.
In terms of revenue, North America dominated the global market and is anticipated to record the highest growth during the forecast period. This is the result of concurrent efforts by both established and emerging players to expand their reagents portfolio. The launch of NGS library preparation kits in September 2018 by clonal Technology signifies this trend.
The Asia-Pacific region is anticipated to experience profitable growth soon. China and Japan have integrated high throughput technologies as a result of significant investments and funding in genetics research. This has increased the use of sequencing technologies in Asia and the Pacific.
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